SYNONYM: HYDROXYTETRACYCLINE MONOHYDROCHLORIDE;
5-HYDROXYTETRACYCLINE HYDROCHLORIDE; MEDEMYCIN;
FORMULA: C22H25ClN2O9
M. W.: 496.90
CAS NO.: 2058-46-0
GRADE: BP2000/USP24
DESCRIPTION: A YELLOW CRYSTALLINE
POWDER. IDENTIFICATION IS POSITIVE.
SPECIFICATIONS:
|
ITEM |
BP2000 |
USP24 |
|
IDENTIFICATION |
A. B. C. POSITIVE |
A. ABSORPTIVITY
88.2-96.8% (335nm) B. POSITIVE |
|
PH VALUE |
2.4-2.9 |
2.0-3.0 |
|
LOSS ON DRYING |
--- |
2.0% MAX. |
|
SPECIAL OPTICAL ROTATION |
-188o—200o |
--- |
|
ABSORBANCE |
270-290 |
--- |
|
LIGHT0ABSORBING IMPURITIES |
430nm≤0.50 490nm≤0.20 |
--- |
|
RELATED SUBSTANCE |
4-EPIOXYTETRACYCLINE≤0.5% |
--- |
|
TETRACYCLINE≤2.0% |
||
|
THE TOTAL AREA OF THE PEAKS
OF (αTOβ)-APO-OXYTETRACYCLINE≤2.0% |
||
|
THE AREA OF ANY PEAK
APPEARING ON THE TAIL OF THE MAIN PEAK≤2.0% |
||
|
HEAVY METALS |
50PPM MAX. |
--- |
|
WATER |
2.0% MAX. |
--- |
|
SULPHATE ASH |
0.5% MAX. |
--- |
|
POTENCY (HPLC) (μg/mg) |
--- |
835 MIN. (ANHYDROUS) |
|
ASSAY (HPLC) |
95.0-100.5% (ANHYDROUS) |
--- |
PACKING: PACKED IN 25KGS CARDBOARD
DRUM. 9MT/FCL.